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Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name and works the same way in the body in the same amount of time. The only differences between generics and their brand-name counterparts is the generics are less expensive and may look slightly different (e.g. different shape or color), as trademark laws prevent a generic from looking exactly like the brand-name drug. Generics are less expensive because generic manufacturers don't have to invest large sums of money to invent a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name drug and sell it at substantial discounts. (Rx) - indicates only available by prescription Paxil Description Paxil is an antidepressant classed as a 'serotonin selective reuptake inhibitor' (SSRI). Paxil contains the active ingredient called paroxetine, which works to block the clearance of serotonin in brain cells. Depression is associated with an imbalance of serotonin, and thus SSRIs may alleviate the symptoms of depression by regulating serotonin levels in the brain. SSRIs have also been shown to help manage other conditions, such as obsessive compulsive disorder (OCD), panic attacks, and generalized anxiety disorders. Paroxetine may also be prescribed for other medical conditions, such as severe premenstrual syndrome (premenstrual dysphoric disorder), premature ejaculation, diabetic neuropathies, chronic headaches, or post-traumatic stress disorder (PTSD). Paxil Directions Please take this medicine as directed by your doctor. If it comes with an information leaflet, please read this carefully and clarify and queries with your doctor, nurse or pharmacist. Please store paroxetine at room temperature at 77 degrees F (25 degrees C) in a tightly closed container, and also away from direct heat or light. If required, this medicine may be temporarily stored between 59-86 degrees F (15-30 degrees C). Take this medication regularly, do not miss any doses, and do not stop taking this medicine even if you feel better. If you miss a morning dose, then take your dose in the afternoon if you remember. If you don't remember until the next morning, then skip your missed dose and carry on with your regular dose schedule. If you miss a bedtime dose and you take only one dose daily, and you don't remember until the next morning, skip your missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Paxil Cautions If you have experienced any allergies to paroxetine or ingredients in this product, do not take this medicine and consult with your doctor. It is important that prior to taking this medicine, you have discussed your past psychiatric history with your doctor. This includes previous episodes of depression or anxiety attacks, any family members with a psychiatric disorder (e.g. bipolar disorder, depression), as well as a family history of suicide/suicide attempts. It is also important that you have discussed your past medical history with your doctor, in particular: seizures, stomach ulcers, thyroid problems, liver problems, heart problems, kidney problems, glaucoma (narrow angle type). Paxil or Paroxetine may cause you to become drowsy or dizzy, so it is advised that you refrain from driving, or operating machinery. Avoid alcohol as this will exacerbate these side effects. Please take caution if this drug is used in the elderly, as they may be more sensitive to the side effects. If the patient is taking a diuretic ("water pills"), this may interact with paroxetine to cause an electrolyte imbalance. Please consult with your doctor if you are taking these pills. If you wish to become pregnant, please discuss this with your doctor. Paroxetine should not be taken during the first three months or last three months of pregnancy. Taking paroxetine during the first three months has an association with fetal heart defects and other serious abnormalities. Babies born to mothers who have taken paroxetine during the last three months may infrequently develop symptoms including seizures, muscle stiffness, feeding/breathing difficulties, jitteriness or constant crying. If you notice any such symptoms in your new born, consult a doctor immediately. Paroxetine passes into breast milk, and due to the potential risks to the infant, it is advised that you do not breast feed while taking this medication. Paxil Side Effects Paroxetine is associated with some minor side effects that usually subside with treatment. These include weakness, nervousness, fatigue, drowsiness, nausea, vomiting, diarrhea, loss of appetite, dry mouth, sweating, dizziness, lightheadedness, or changes in sexual function. See your doctor if these symptoms continue, or if they are distressing for you. There are different types of anti depressants that differ in their potential side effects. If the disadvantages of this medicine outweigh the advantages, there may be another antidepressant more suited for you. Please discuss this with your doctor. Please see your doctor immediately if you experience any of the following: difficulty sleeping, seizures, unusual bleeding or bruising, anxiety, severe nervousness, agitation, panic attacks, feelings of irritability or hostility, impulsive behavior or other unusual changes in behavior, severe restlessness, worsening feelings of depression, thoughts of hurting yourself, or any other mental or mood changes. For men: If you experience a prolonged, painful erection, stop using this medicine and seek immediate medical attention or permanent problems could occur. Although it is unlikely to occur, please be aware of the signs of an allergic reaction. 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Symptoms of Paxil withdrawal include: Dizziness and vertigo; Paxil CR 12.5 mg, Paroxetine 12.5 mg ER-MYL. Drug information on Paxil, Paxil CR, Pexeva paroxetine, includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what. In order to use Medscape, your browser must be set to accept cookies delivered by the Medscape site. To find out how to adjust your browser settings to accept cookies, please click here. Medscape uses cookies to customize the site based on the information we collect at registration. The cookies contain no personally identifiable information and have no effect once you leave the Medscape site. You can read more about our use of cookies in our privacy policy. 7 risk of withdrawal 12 Several studies have associated paroxetine Postmortem blood levels have ranged from 1–4 mg/L in acute lethal. From people going through paxil withdrawal that I have received taking Paxil CR 12.5 mg/day. She mentioned from reading the stories. Common side effects of Paxil-CR The recommended dose of Paxil-CR is 12.5-75 mg as a paroxetine hydrochloride Side Effects Drug Center provides a. This eMedTV resource describes other possible Paxil CR withdrawal symptoms and explains what your doctor may do to keep Paxil CR paroxetine controlled. Medscape - Depression-specific dosing for Paxil, Paxil CR paroxetine, frequency-based adverse effects, Paxil CR: 12.5 mg PO qDay initially; may titrate;. Pill imprint PAXIL CR 12.5 has been identified as Pill imprint PAXIL CR 12.5 has been identified as Paxil CR 12.5 mg. Paxil CR is used in the treatment of. Pill imprint PAXIL CR 12.5 has been identified as Paxil CR 12.5 mg. Paxil CR is used in the treatment of anxiety; generalized anxiety disorder; depression; panic disorder; dysautonomia (and more), and belongs to the drug class selective serotonin reuptake inhibitors. Excluding Brisdelle: There is positive evidence of human fetal risk during pregnancy. Brisdelle: Not for use in pregnancy. Paxil CR 12.5 mg is not a controlled substance under the Controlled Substance Act (CSA). Save money when safely buying Paxil online. PlanetDrugsDirect is a safe and secure Canadian international prescription referral service. Ask Our Pharmacist about Paxil Medication Canada Drugs believes access to essential prescription drugs should be safe, convenient, and affordable for all and because of this belief we work hard to maintain extremely rigorous standards of patient safety and security. When you order discount Paxil from our pharmacy, you are guaranteed the lowest price available for Paxil medication, free shipping and an unmatched No-Risk Guarantee . Buy Paxil Prescriptions Online at the lowest price guaranteed at CanadianPharmacyMeds.com. A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, how it is taken, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name and works the same way in the body in the same amount of time. The only differences between generics and their brand-name counterparts is the generics are less expensive and may look slightly different (e.g. different shape or color), as trademark laws prevent a generic from looking exactly like the brand-name drug. Generics are less expensive because generic manufacturers don't have to invest large sums of money to invent a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name drug and sell it at substantial discounts. (Rx) - indicates only available by prescription Paxil Description Paxil is an antidepressant classed as a 'serotonin selective reuptake inhibitor' (SSRI). Paxil contains the active ingredient called paroxetine, which works to block the clearance of serotonin in brain cells. Depression is associated with an imbalance of serotonin, and thus SSRIs may alleviate the symptoms of depression by regulating serotonin levels in the brain. SSRIs have also been shown to help manage other conditions, such as obsessive compulsive disorder (OCD), panic attacks, and generalized anxiety disorders. Paroxetine may also be prescribed for other medical conditions, such as severe premenstrual syndrome (premenstrual dysphoric disorder), premature ejaculation, diabetic neuropathies, chronic headaches, or post-traumatic stress disorder (PTSD). Paxil Directions Please take this medicine as directed by your doctor. If it comes with an information leaflet, please read this carefully and clarify and queries with your doctor, nurse or pharmacist. Please store paroxetine at room temperature at 77 degrees F (25 degrees C) in a tightly closed container, and also away from direct heat or light. If required, this medicine may be temporarily stored between 59-86 degrees F (15-30 degrees C). Take this medication regularly, do not miss any doses, and do not stop taking this medicine even if you feel better. If you miss a morning dose, then take your dose in the afternoon if you remember. If you don't remember until the next morning, then skip your missed dose and carry on with your regular dose schedule. If you miss a bedtime dose and you take only one dose daily, and you don't remember until the next morning, skip your missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Paxil Cautions If you have experienced any allergies to paroxetine or ingredients in this product, do not take this medicine and consult with your doctor. It is important that prior to taking this medicine, you have discussed your past psychiatric history with your doctor. This includes previous episodes of depression or anxiety attacks, any family members with a psychiatric disorder (e.g. bipolar disorder, depression), as well as a family history of suicide/suicide attempts. It is also important that you have discussed your past medical history with your doctor, in particular: seizures, stomach ulcers, thyroid problems, liver problems, heart problems, kidney problems, glaucoma (narrow angle type). Paxil or Paroxetine may cause you to become drowsy or dizzy, so it is advised that you refrain from driving, or operating machinery. Avoid alcohol as this will exacerbate these side effects. Please take caution if this drug is used in the elderly, as they may be more sensitive to the side effects. If the patient is taking a diuretic ("water pills"), this may interact with paroxetine to cause an electrolyte imbalance. Please consult with your doctor if you are taking these pills. If you wish to become pregnant, please discuss this with your doctor. Paroxetine should not be taken during the first three months or last three months of pregnancy. Taking paroxetine during the first three months has an association with fetal heart defects and other serious abnormalities. Babies born to mothers who have taken paroxetine during the last three months may infrequently develop symptoms including seizures, muscle stiffness, feeding/breathing difficulties, jitteriness or constant crying. If you notice any such symptoms in your new born, consult a doctor immediately. Paroxetine passes into breast milk, and due to the potential risks to the infant, it is advised that you do not breast feed while taking this medication. Paxil Side Effects Paroxetine is associated with some minor side effects that usually subside with treatment. These include weakness, nervousness, fatigue, drowsiness, nausea, vomiting, diarrhea, loss of appetite, dry mouth, sweating, dizziness, lightheadedness, or changes in sexual function. See your doctor if these symptoms continue, or if they are distressing for you. There are different types of anti depressants that differ in their potential side effects. If the disadvantages of this medicine outweigh the advantages, there may be another antidepressant more suited for you. Please discuss this with your doctor. Please see your doctor immediately if you experience any of the following: difficulty sleeping, seizures, unusual bleeding or bruising, anxiety, severe nervousness, agitation, panic attacks, feelings of irritability or hostility, impulsive behavior or other unusual changes in behavior, severe restlessness, worsening feelings of depression, thoughts of hurting yourself, or any other mental or mood changes. For men: If you experience a prolonged, painful erection, stop using this medicine and seek immediate medical attention or permanent problems could occur. Although it is unlikely to occur, please be aware of the signs of an allergic reaction. If you experience any of the following, please seek immediate medical attention: difficulty breathing, dizziness, rash, itching, or swelling of the face/throat. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist. Purchase brand Paxil or generic Paroxetine at heavily discounted rates from our online pharmacy.','url':'https://www.planetdrugsdirect.com/drugs/paxil','og_descr':'Save money when safely buying Paxil online. PlanetDrugsDirect is a safe and secure Canadian international prescription referral service. Buy Paxil. Paxil is a trade name for the SSRI selective serotonin reuptake inhibitor antidepressant paroxetine hydrochloride. Other trade names are Aropax and Seroxat. Since the dose is product is not manufactured dose of levitra buy online no prescription http hamster ovary cell line mite is made by where can you buy lip balm.
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Our staff of licensed, accredited pharmacists and technicians will make sure the Paxil discount prescription drugs that you order through us are the right product for you by reviewing the prescription you have sent us from your doctor. Just like at your local pharmacy our pharmacists will assess prescription accuracy, any possible drug interactions and the appropriateness of therapy. Our pharmacists are also available to answer any questions and provide counseling services to ensure that you are empowered and knowledgeable about your Paxil and how they fit into your overall health. If you have any questions about buying discount Paxil online or any other prescription products you can contact our team of professional Patient Service Representatives or one of our pharmacists 24-7 by calling 1-800-226-3784. Notice: The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. 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Paxil paroxetine is a prescription drug in the SSRI category of antidepressants. Doctors prescribe paroxetine to treat depression, anxiety disorders, and menopause. Social Anxiety Disorder: Paxil may relieve feelings of More common side effects may include: weakness, The recommended starting dose is 20 milligrams mg. In general, the recommended starting Paxil® (paroxetine hydrochloride) dose for treating various conditions of the brain is Paxil 20 mg tablets once daily (usually in the morning). However, the dose of Paxil your healthcare provider recommends will vary depending on a number of factors, such as your age, other medical conditions you may have, and other medications you are currently taking (including vitamins and herbal supplements). The starting dose for treating panic disorder and for elderly people or people with liver or kidney problems is typically lower: Paxil 10 mg once daily. Your healthcare provider may choose to increase the Paxil dosage if symptoms continue, or decrease the dose if side effects occur. The maximum Paxil dose is 50 mg (for depression, generalized anxiety disorder, or post-traumatic stress disorder) or 60 mg (for social anxiety disorder, panic disorder, or obsessive-compulsive disorder). It usually takes several weeks (perhaps even more than a month) before feeling the beneficial effects of Paxil. Try not to be discouraged if the medication does not work right away for you. (Click Paxil Dosage for more information on using Paxil for treating conditions such as depression, obsessive-compulsive disorder, and certain anxiety disorders. This article also offers tips on effectively using the medication.) In order for us to best serve you and provide you with the best information, can you please tell us if you currently have health insurance? In order for us to create your customized HealthSavvy programs, we need a little more information about the health topic(s) that you are interested in. Press "Continue" button below to begin selecting your HealthSavvy topic(s).','url':'http://anxiety.emedtv.com/paxil/paxil-20-mg-tablets.html','og_descr':'As this eMedTV Web article explains, a healthcare provider may prescribe Paxil 20 mg tablets once daily to treat several conditions, including depression and anxiety. This page also lists factors that may affect your dosage of Paxil. Nov 29, 2015 Learn about indications, dosage and how it is supplied for the drug Paxil Paroxetine Hydrochloride. Pill imprint PAXIL 40 has been identified as Paxil Pill imprint PAXIL 40 has been identified as Paxil 40 mg. Paxil is used in the treatment of anxiety and stress;. Tell your doctor if you use or have ever used illegal or recreational drugs or abused prescription medications. The recommended daily dose of paroxetine is 40 mg. Nov 28, 2015 and 40 mg/day of PAXIL with paroxetine hcl oral; Paxil Side Effects You are encouraged to report negative side effects of prescription drugs. More common side effects may include: weakness, sweating, The recommended starting dose is 10 mg once a day. Swallow Paxil tablets whole. Transcript PATIENT INFORMATION LEAFLET Paroxetine 20mg and 40mg Tablets Paroxetine Read all of this leaflet carefully before you start taking this medicine. Keep this leaflet. You may need to read it again. If you have any further questions, ask your doctor or pharmacist. This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. In this leaflet: 1 2 3 What Paroxetine is and what it is used for Before you take Paroxetine How to take Paroxetine 4 5 6 Possible side effects How to store Paroxetine Further information Using other medicines Certain other medicines may influence the effect of Paroxetine, or Paroxetine may influence their effects. Some Paroxetine belongs to a group of medicines called selective of the medicines in question are listed below: serotonin reuptake inhibitors (SSRIs), which are antidepressants. Tricyclic antidepressant (against depression) e.g. clomipramine, nortriptyline and desipramine Paroxetine is used in the treatment of: SSRI’s e.g. citalopram and fluoxetine Depressive illness (major depressive episodes) L−tryptophan (against sleep disturbances) Obsessive compulsive disorder (compulsive thoughts MAO−inhibitors (e.g. against depression or Parkinson) and compulsive actions) OCD Lithium (antipsychotic) Panic disorder with or without agoraphobia (e.g. fear of St. John’s Wort (Hypericum perforatum) leaving the house, entering shops, or fear of public places) Triptans (against migraine) Social phobia Tramadol and pethidine (potent painkiller) Generalised anxiety disorder Fentanyl (used in anaesthesia or to treat chronic pain) Post−traumatic stress disorder Linezolid (antibiotic) Concomitant use of above mentioned medicinal products 2 Before you take Paroxetine may e.g. lead to "serotonine syndrome" by potentiating serotonergic effects of Paroxetine (see "Do not take Do not take Paroxetine Paroxetine" and "Take special care with Paroxetine"). if you are allergic to paroxetine, or any of the other Your doctor will want to monitor you more closely. ingredients of the product. Perphenazine, risperidone, thioridazine, pimozide and if you are taking the medicines MAO−inhibitors (e.g. clozapine (antipsychotics) against depression) concomitantly or have taken Propafenone and flecainide (against irregular heart rhythm) MAO−inhibitors within the two last weeks. Metoprolol (heart medicines) An exception is moclobemide and linezolid where Concomitant use of above mentioned medicinal Paroxetine treatment can be initiated after 24 hours. At products may lead to an increased rate of side effects least one week should elapse between discontinuation of of these such as cardiac effects, which in some cases Paroxetine and initiation of therapy with any MAO−inhibitor. may be severe (see "Do not take Paroxetine"). if you take thioridazine (antipsychotic agent) concomitantly Phenobarbital, carbamazepine and phenytoin (against if you take pimozide (antipsychotic agent) concomitantly epilepsy) Rifampicin (antibiotic) Take special care with Paroxetine: Concomitant use of above mentioned medicinal Use in children and adolescents under 18 years of age products may weaken the effect of Paroxetine by Paroxetine should not normally be used for children and increasing the metabolism of paroxetine. adolescents under 18. Clinical trials have shown that NSAIDs (e.g. ibuprofen, diclofenac), COX−2 inhibitors patients under 18 have an increased risk of side effects and acetylsalicylic acid (aspirin) (painkillers) such as suicide attempt, suicidal thoughts and hostility Warfarin or other medicines used to prevent blood clotting (predominantly aggression, oppositional behaviour and Clozapine, phenothiazines (antipsychotics) and most anger) when they take this class of medicines. tricyclic antidepressants (against depression) Despite this, your doctor may prescribe Paroxetine for Concomitant use of above mentioned medicinal patients under 18 because he/she decides that this is products may lead to increased/prolonged bleeding in their best interest. If your doctor has prescribed (see "Take special care with Paroxetine"). Paroxetine for a patient under 18 and you want to discuss Procyclidine (against Parkinson disease). Increased this, please go back to your doctor. side effects of procyclidine may occur by increasing the You should inform your doctor if any of the listed above concentration of procyclidine in the blood. develop or worsen when patients under 18 are taking Tamoxifen, (to treat breast cancer or fertility problems). Paroxetine. Also, the long−term safety effects concerning Concomitant use may reduce the effectiveness of growth, maturation and cognitive and behavioural tamoxifen. development of this age group have not yet been Combination of fosamprenavir and ritonavir (to treat HIV demonstrated. infection) Thoughts of suicide and worsening of your Atomoxetine (to treat attention deficit hyperactivity depression or anxiety disorder disorder (ADHD)) If you are depressed and/or have anxiety disorders you Please tell your doctor or pharmacist if you are taking or can sometimes have thoughts of harming or killing have recently taken any other medicines, including yourself. These may be increased when first starting medicines obtained without a prescription. antidepressants, since these medicines all take time to work, usually about two weeks but sometimes longer. Taking Paroxetine with food and drink You may be more likely to think like this: Alcohol: The combination of Paroxetine and alcohol is not − if you have previously had thoughts about killing or recommended. harming yourself. Pregnancy and breast−feeding − if you are a young adult. Information from clinical trials has shown an increased Ask your doctor or pharmacist for advice before taking any medicine. risk of suicidal behaviour in adults aged less than 25 years with psychiatric conditions who were treated with Pregnancy: Talk to your doctor as soon as possible if you are planning to an antidepressant. − If you have thoughts of harming or killing yourself at any get pregnant or if you are already pregnant. time, contact your doctor or go to a hospital straight In babies whose mothers took Paroxetine during the first few away. months of pregnancy, there have been some reports showing an increased risk of birth defects, in particular those affecting You may find it helpful to tell a relative or close friend that the heart. In the general population, about 1 in 100 babies are you are depressed or have an anxiety disorder, and ask born with a heart defect. This increased to about 2 in 100 them to read this leaflet. You might ask them to tell you if babies in mothers who took Paroxetine. You and your doctor they think your depression or anxiety is getting worse, or if may decide that it is better for you to gradually stop taking they are worried about changes in your behaviour. Paroxetine while you are pregnant. However, depending on Withdrawal symptoms seen on a discontinuation of a your circumstances, your doctor may suggest that it is better for selective serotonin reuptake inhibitor (SSRI) you to keep taking Paroxetine. When you stop taking Paroxetine, especially if it is abruptly, Make sure your midwife and/or doctor know you are on you may feel discontinuation symptoms (see "How to take Paroxetine" and "Possible side effects"). These are Paroxetine. When taken during pregnancy, particularly in the last 3 months of pregnancy, medicines like Paroxetine may common when treatment is stopped. The risk is higher, increase the risk of a serious condition in babies, called when Paroxetine has been used for a long time or in a persistent pulmonary hypertension of the new born (PPHN), high doses or when the dose is reduced too quickly. making the baby breathe faster and appear bluish. These Most people find that the symptoms are mild and go symptoms usually begin during the first 24 hours after the away on their own within two weeks. However, in some baby is born. If this happens to your baby you should contact patients they may be severe in intensity or they may be your midwife and/or doctor immediately. prolonged (2−3 months or more). 1 What Paroxetine is and what it is used for If you get severe discontinuation symptoms when you stop taking Paroxetine, please contact your doctor. He or she may ask you to start taking your tablets again and come off them more slowly. Check with your doctor if: you develop symptoms such as inner sense of restlessness and psychomotor agitation such as an inability to sit or stand still usually associated with subjective distress (akathisia). This is most likely to occur within the first few weeks of treatment. Increasing the dose of Paroxetine may make these feelings worse (see section "Possible side effects"). you develop symptoms such as high fever, muscle cramps, confusion and anxiety since these symptoms could be a sign of so called "serotonin syndrome". Therefore Paroxetine should not be used in combination with other medicines with serotonergic effects such as sumatriptan or other triptans (certain migraine medicines), tramadol, linezolid, other SSRIs, lithium and St. John’s Wort (Hypericum perforatum), oxitriptan and tryptophan. you have a history of mania (overactive behaviour or thoughts). If you are entering a manic phase, you should stop taking Paroxetine. Ask your doctor for advice. you have heart, liver or kidney problems. In patients with severe kidney disorder or those with liver disorder a dose reduction is recommended. you have diabetes. Paroxetine can raise or lower your blood sugar. The dose of your insulin or anti−diabetes medicine taken orally may need to be adjusted. you have epilepsy. If you develop seizures during treatment with Paroxetine, you should contact your doctor. your treatment for depression is electro convulsive therapy, (ECT). you have glaucoma (elevated pressure in your eyes) you are at risk of a decreased sodium level in the blood (hyponatraemia) e.g. from concomitant medications and cirrhosis. Hyponatraemia has been reported rarely during treatment with Paroxetine, predominantly in the elderly. you have a history of bleeding disorder e.g. cutaneous bleeding abnormalities, gynaecological or haemorrhage from the stomach or if you use medicines which possibly increase tendency to bleed (see section "Taking other medicines"). Please consult your doctor, even if these statements were applicable to you at any time in the past. If you are taking Paroxetine in the last 3 months of pregnancy your newborn baby might also have other conditions which usually begin during the first 24 hours after birth. Symptoms include not being able to sleep or feed properly, trouble with breathing, a blue−ish skin or being too hot or cold, being sick, crying a lot, stiff or floppy muscles, tiredness, lack of energy, trembling of the body, jitters or fits. If your baby has any of these symptoms when it is born, contact your doctor who will be able to advise you. Breast−feeding: Although small amounts of Paroxetine pass into breast milk, studies did not show any effect on babies. You and your doctor may decide that you can breast−feed while you are taking Paroxetine. Fertility: Paroxetine has been shown to reduce the quality of sperm in animal studies. Theoretically, this could affect fertility, but impact on human fertility has not been observed as yet. Driving and using machines Paroxetine may cause side effects (such as feeling dizzy, sleepy, or confused) that affect how well you concentrate and how quickly you can react. If you get these side effects, do not drive or operate machines, or anything else where you need to be alert and concentrate. 3 How to take Paroxetine Always take Paroxetine exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. The tablets should be taken in the morning with your breakfast. Drink a glass of water with your medicine. The tablet or tablet halves should be swallowed rather than chewed. The usual dose is: Adults Depression The recommended dose is 20 mg daily. Depending on your response, the dose may be increased gradually up to a maximum dose of 50 mg daily in 10 mg steps. In general, improvement in patients starts after one week but may only become evident from the second week of therapy. The treatment should be continued for several months. continued.... Hard to Read? Phone 0800 970 6115 for help Till−Ver.3s Obsessive thoughts and obsessive actions (OCD) The initial dose is 20 mg daily. Depending on your response, the dose may be increased gradually to 40 mg daily in 10 mg steps. The recommended dose is 40 mg daily. The maximum dose is 60 mg daily. The treatment should be continued for several months. Panic disorder The initial dose is 10 mg daily. Depending on your response, the dose may be gradually increased to 40 mg daily in 10 mg steps. The recommended dose is 40 mg daily. The maximum dose is 60 mg daily. The treatment should be continued for several months. Social phobia, generalised anxiety disorder and post− traumatic stress disorder The recommended dose is 20 mg daily. Depending on your response, the dose may be increased gradually to 50 mg in 10 mg steps. The maximum dose is 50 mg daily. Elderly (more than 65 years) Depending on your response the dose may be increased to 40 mg daily. The maximum dose is 40 mg daily. Severe decreased kidney function Your doctor prescribes a suitable dose for you. Decreased liver function Your doctor prescribes a suitable dose for you. If you take more Paroxetine than you should If you have taken more Paroxetine than you should, talk to your doctor or pharmacist, or contact with the nearest hospital. Symptoms of overdose are e.g. being sick, fever, headache and involuntary muscle contractions. If you forget to take Paroxetine If you forget to take a dose, and you remember before you go to bed, take it straight away. Carry on as usual the next day. If you only remember during the night, or the next day, leave out the missed dose. You may possibly get withdrawal effects, but these should go away after you take your next dose at the usual time. If you stop taking Paroxetine Do not stop taking Paroxetine until your doctor tells you to, even if you feel better. If you stop suddenly after taking this medicine for a long time you can experience withdrawal effects. When stopping treatment with Paroxetine the dose should be gradually reduced over a period of several weeks or 2 − 3 months or more in order to reduce the risk of withdrawal reactions (for withdrawal symptoms see section "Possible side effects"). One way of doing this is to gradually reduce the dose of Paroxetine you take by 10 mg a week. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, your doctor may ask you to start taking you tablets again and come off them more slowly. If you have any further questions on the use of this product, ask your doctor or pharmacist. What to do if you feel no better Paroxetine will not relieve your symptoms straight away − all antidepressants take time to work. Some people will start to feel better within a couple of weeks, but for others it may take a little longer. Some people taking antidepressants feel worse before feeling better. If you do not start to feel better after a couple of weeks, go back to your doctor who will advise you. Your doctor should ask to see you again a couple of weeks after you first start treatment. Tell your doctor if you have not started to feel better. 4 Possible side effects Like all medicines, Paroxetine can cause side effects, although not everybody gets them. You should see your doctor immediately if you experience symptoms such as: swollen face, tongue and/or throat and/or difficulty to swallow or itchy rash together with difficulties to breathe (angioedema) high fever, muscle cramps, confusion and anxiety since these symptoms could be a sign of so called "serotonin syndrome" If you develop suicidal thoughts or suicidal ideation during treatment with Paroxetine, especially in the first 2−4 weeks, you should contact your doctor immediately. Other side effects If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. Frequencies are defined as: very common (occurs in more than one in 10 patients), common (occurs in more than one in 100, but less than one in 10 patients), uncommon (occurs in more than one in 1000, but less than one in 100 patients), rare (occurs in more than one in 10,000, but less than one in 1000 patients), very rare (occurs in less than one in 10,000 patients, including isolated reports). not known (cannot be estimated from the available data). Blood and lymphatic system disorders Uncommon: abnormal bleeding, predominantly of the skin and mucous membranes (mostly ecchymosis) Very rare: deficiency of blood platelets Immune system disorders Very rare: allergic reactions including nettle rash (urticaria) and swelling of the face, lips, tongue or throat with difficulty to breathe or swallow (angioedema) Hormone (endocrine) disorders Very rare: syndrome of inappropriate anti−diuretic hormone secretion (SIADH) Metabolism and nutrition disorders Common: decreased appetite, increase in cholesterol levels Rare: reduced sodium level in the blood (hyponatraemia). Hyponatraemia has been reported predominantly in elderly patients and is sometimes due to syndrome of inappropriate anti−diuretic hormone secretion (SIADH). Psychiatric disorders Common: somnolence, insomnia, agitation, abnormal dreams (including nightmares) Uncommon: confusion, hallucinations Rare: overactive behaviour or thoughts (manic reactions), anxiety, feeling detached from yourself (depersonalisation), panic attacks, feeling restless and unable to sit or stand still (akathisia) Frequency not known: Cases of suicidal ideation and suicidal behaviours have been reported during paroxetine therapy or early after treatment discontinuation (see section ’Take special care with Paroxetine’). These symptoms may also be due to the underlying disease. Cardiac disorders Uncommon: rapid heart rate Rare: slow heart rate Vascular disorders Uncommon: temporary increases or decreases in blood pressure, especially when going from lying or sitting position to standing up and usually in patients with pre− existing high blood pressure (hypertension) or anxiety. Respiratory, thoracic and mediastinal disorders Common: yawning Gastrointestinal disorders Very common: feeling sick (nausea) Common: constipation, diarrhoea, dry mouth, being sick Very rare: bleeding in the stomach or intestine Liver/bile (hepato−biliary disorders) Rare: elevation of liver enzymes Very rare: liver disorder (such as hepatitis, sometimes associated with jaundice and/or liver failure) Skin and subcutaneous tissue disorders Common: sweating Uncommon: skin rashes, itching Very rare: hypersensitivity to sunlight Renal and urinary disorders Uncommon: inability to urinate (urinary retention) or an uncontrollable, involuntary passing of urine (urinary incontinence). Reproductive system and breast disorders Very common: sexual dysfunction Rare: too much of prolactin, a lactation hormone, in the blood (hyperprolactinaemia), breast discharge Very rare: painful erection of the penis that won’t go away Musculoskeletal and connective tissue disorders Rare: joint pain, muscle pain An increased risk of bone fractures has been observed in patients taking this type of medicine. General disorder and administration site conditions Common: general disability, body weight gain Very rare: swelling of the tissue caused by fluid retention Withdrawal symptoms seen on discontinuation of Paroxetine treatment Withdrawal reactions commonly occur after discontinuation of Paroxetine (see sections "Before you take Paroxetine" and "How to take Paroxetine"). Dizziness, sensory disturbances (including tingling or numbness in the hands or feet, electric shock sensations and ringing in the ears), sleep disturbances (including insomnia and intense dreams), agitation or anxiety, feeling sick (nausea) and/or being sick (vomiting), trembling of the body (tremor), confusion, sweating, emotional instability, visual disturbances, fluttering or pounding heartbeat (palpitations), diarrhoea, irritability and headache are the most commonly reported reactions. Generally these events are mild to moderate and are self− limiting, however, in some patients they may be severe and/or prolonged. Children and adolescents under 18 In studies of Paroxetine in under 18s, the following side effects were observed: increased suicidal related behaviours (including suicide attempts and suicidal thoughts), self−harm behaviours and increased hostility. Additional side effects that were seen were: decreased appetite, trembling of the body, sweating, having too much energy (hyperkinesias or hyperactivity), agitation, changing emotions (including crying and mood fluctuations) and unusual bruising or bleeding (such as nose bleeds). In studies, some patients had withdrawal effects when they stopped taking Paroxetine or gradually reduced the dose before stopping, as follows: changing emotions (including crying, mood fluctuations, self−harm, suicidal thoughts and attempted suicide), nervousness, dizziness, feeling sick and abdominal pain. 5 How to store Paroxetine Do not use Paroxetine after the expiry date which is stated on the carton or blister respectively. The expiry date refers to the last day of that month. Do not store above 30°C (for product available in blister packs). Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment. 6 Further information What Paroxetine 20 mg and 40 mg contain The active substance is paroxetine Each tablet contains 20 mg or 40 mg paroxetine equivalent to 22.2 mg or 44.4 mg of paroxetine hydrochloride anhydrate The other ingredients are: Tablet core Mannitol Cellulose, microcrystalline Copovidone Sodium starch glycollate (Type A) Silica, colloidal anhydrous Magnesium stearate Tablet coating Hypromellose Talc (micronised) Titanium dioxide (E171) What Paroxetine looks like and contents of the pack Paroxetine 20 mg is a white, round bisected film−coated tablet with a pressure sensitive score notch, marked "PX 20" The 20 mg tablet can be divided into equal halves, if required. Paroxetine 40 mg is a white, round, quadrisected film− coated tablet with a pressure sensitive score notch, marked "PX 40" The 40 mg tablet can be divided into equal quarters, if required. The 20 mg and 40 mg tablets are available in blister packs or containers with 7, 14, 15, 20, 28, 30, 40, 50, 50x1, 60, 100, 200 and 250 film−coated tablets. The 20mg tablets are also available in blister packs or containers with 10 film−coated tablets Not all pack sizes may be marketed. Nervous system disorders Common: dizziness, trembling of the body (tremor), headache Uncommon: slow or/and involuntary movements (extrapyramidal disorders) Rare: irresistible urge to move the legs (Restless Legs Syndrome), convulsions Very rare: serotonin syndrome (symptoms may include restlessness, confusion, sweating, hallucinations, exaggeration of reflexes, muscle cramps, shivering, rapid heart rate and trembling of the body). Marketing Authorisation Holder and Manufacturer Tillomed Laboratories Ltd 3 Howard Road, Eaton Socon, St. Neots, Cambridgeshire, PE19 8ET Eye disorders Common: blurred vision Uncommon: enlarged pupils (mydriasis) Very rare: increased pressure in the eye where your eyes become painful and you get blurred vision (acute glaucoma) Date of revision: June 2012 Product Licence Number: Paroxetine 20mg tablets: PL 11311/0402 Paroxetine 40mg tablets: PL 11311/0403 Ear disorders Frequency not known: Ringing in the ears (tinnitus) Hard to Read? Phone 0800 970 6115 for help Till−Ver.3s Product Name Strength / Form Type Dimensions Typefaces Rev # Last updated No. of Colours Paroxetine Combined PIL Tablets PIL 175 mm x 510 mm Font SansSerif − Min.Text 8pt Till−Ver.3s 05/07/2012 Pantone Black CVC Tillomed Laboratories Ltd, 3 Howard Road Eaton Socon, St Neots, Cambs PE19 8ET, UK Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.','url':'http://www.drugs.com/uk/paroxetine-40-mg-tablets-leaflet.html','og_descr':'Patient information for PAROXETINE 40 MG TABLETS Including dosage instructions and possible side effects. Paxil (Paroxetine) Patient information for PAROXETINE 40 MG TABLETS Including dosage instructions and possible side effects. Skip to Content What Paroxetine 20 mg and 40 mg contain. Paxil is also approved by Food and Drug Administration (FDA) to help women manage the hot flashes associated with menopause. Additionally, doctors may prescribe Paxil off-label to treat conditions other than those for which it has been approved by the FDA. For example, some doctors prescribe Paxil to treat chronic headaches, and people with diabetes may use the drug to help alleviate tingling in the hands and feet. Paxil has also been used to treat men who experience premature ejaculation. A controlled-release form, Paxil CR, can relieve the physical and psychological symptoms some women experience before their menstrual cycle begins each month. Paxil belongs to a class of antidepressant medications called selective serotonin-reuptake inhibitors (SSRIs ). SSRIs work by boosting levels of serotonin, a neurotransmitter that helps the brain send messages from one nerve cell to another. Paxil History GlaxoSmithKline makes Paxil, which the FDA first approved in 2001. Paxil is also available under the brand names Brisdelle and Pexeva. Generic forms of paroxetine became available in 2003. GlaxoSmithKline has repeatedly come under fire for its marketing of Paxil and other antidepressants, including accusations that the company misreported data from clinical trials, which showed that Paxil might be unsafe for teenagers and young adults. In 2012, GlaxoSmithKline agreed to pay a $3 billion fine to U.S. federal prosecutors, in part for its antidepressant marketing practices. A study published in the medical journal BMJ in 2015 reanalyzed data from 2001 and found that Paxil was ineffective at treating depression in adolescents. Additionally, the study found that use of the drug among adolescents was associated with significant harm, including thoughts of suicide and suicide attempts. Paxil Warnings Paxil and other antidepressants are required to carry a black-box warning because of an increased risk of suicide. A growing body of research shows that some children, teens, and young adults who take an antidepressant drug such as Paxil often develop suicidal thoughts or actions. Young people up to age 24 who take these medications for the treatment of depression or another mental illness have a high risk of suicidal thoughts and behaviors. In some cases, a doctor may determine that the drug is appropriate for someone younger than 18. Children who take paroxetine could lose weight, so their doctor should closely monitor their growth while they are taking the medication. Adults taking Paxil to treat depression or mental illness may also experience unexpected changes in their behavior or mental state. Women taking low doses of the drug to ease the discomfort of hot flashes may also change in their behavior or mental state, even if they have never had depression or another mental illness. People taking Paxil are more likely to become suicidal when they first start taking the medication and whenever their dose of the drug is increased. A 2014 study found that Paxil acts as an estrogen promoter, which could have implications for women with estrogen-sensitive (estrogen-receptor positive) breast cancer . The research also found that Paxil could reduce the effectiveness of the breast cancer drug tamoxifen . Tell your doctor if you have ever had glaucoma or seizures. It's also important to tell your doctor if you have: Paxil paroxetine is a prescription drug in the SSRI category of antidepressants. Doctors prescribe paroxetine to treat depression, anxiety disorders, and menopause. Drug information on Paxil, Paxil CR, Pexeva paroxetine, includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what. Pill imprint PAXIL CR 25 has been identified as Paxil CR paroxetine 25 mg. View images and comprehensive information for this drug. Find patient medical information for Paxil CR oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Learn about the prescription medication Paxil-CR (Paroxetine Hydrochloride), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Depression. Conventional: 20 mg PO qDay initially; may increase by 10 mg/day qWeek not to exceed 50 mg/day. Paxil CR: 25 mg PO qDay initially; may increase by 12.5 mg. Learn about the prescription medication Paxil-CR Paroxetine Hydrochloride, drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. Pill imprint PAXIL CR 25 has been identified as Paxil CR 25 mg. Paxil CR is used in the treatment of anxiety; generalized anxiety disorder; depression; panic disorder; dysautonomia (and more), and belongs to the drug class selective serotonin reuptake inhibitors. Excluding Brisdelle: There is positive evidence of human fetal risk during pregnancy. Brisdelle: Not for use in pregnancy. Paxil CR 25 mg is not a controlled substance under the Controlled Substance Act (CSA). |